The 95-year-old monarch, who tested positive for coronavirus in February, discussed her experience in a video call with staff at an east London hospital on Wednesday.
The Queen said of the virus: "I'm glad that you're getting better...It does leave one very tired and exhausted, doesn't it? This horrible pandemic. It's not a nice result."
The palace previously confirmed both the monarch and her late husband, Prince Philip, received their first doses of a Covid-19 vaccine in January 2021.